A Facile Solvent Free Claisen-Schmidt Reaction: Synthesis of α,α′-bis-(Substituted-benzylidene)cycloalkanones and α,α′-bis-(Substituted-alkylidene)cycloalkanones

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A facile solvent free Claisen-Schmidt reaction: synthesis of α,α'-bis-(substituted-benzylidene)cycloalkanones and α,α'-bis-(substituted-alkylidene)cycloalkanones.

Solvent-free Claisen-Schmidt reactions of cycloalkanones with various substituted benzaldehydes (aryl aldehydes) using solid NaOH (20 mol%) and applying a grinding technique were studied. Quantitative yields (96-98%) of α,α'-bis-(substituted-benzylidene)cycloalkanones were obtained. Aliphatic aldehydes also provided α,α'-bis-(substituted-alkylidene)cycloalkanones in very good yields with minor ...

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Facile and mild synthesis of 1-substituted-1H-1,2,3,4-tetrazoles catalyzed by methanesulfonic acid under solvent-free conditions

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Synthesis of substituted trisphenols by use of a double acidic ionic liquid under solvent-free conditions

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Synthesis of substituted trisphenols by use of a double acidic ionic liquid under solvent-free conditions

3-methyl-1-(4-sulfobuthyl)-1-H-imidazol-3ium hydrogen sulfate, as a dual acidic ionic liquid (DAIL), was found to be an efficient catalyst for the simple, rapid and green synthesis of substituted trisphenols from the condensation of different substituted phenols and 2,6-bis (methylol) phenols (BMP). DAIL catalyst efficiently promoted the reaction between phenols and BMPs with a variety of funct...

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ژورنال

عنوان ژورنال: Molecules

سال: 2012

ISSN: 1420-3049

DOI: 10.3390/molecules17010571